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Structure of 5457-44-3
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Dimethyl 3-oxohexanedioate features a β-keto ester motif flanked by two ester groups, enabling facile enolization and participation in aldol-type condensations. This versatile synthon integrates readily into polyketide scaffolds and supports efficient construction of complex carbocycles under mild conditions.
Dimethyl 3-oxohexanedioate serves as a versatile synthon in carbonylative synthesis, enabling efficient construction of substituted β-keto ester motifs. Its α,β-unsaturated diketone framework facilitates Michael additions, Claisen condensations, and heterocycle formation under mild conditions. The molecule exhibits good bench stability and is readily purified by distillation or recrystallization, making it well-suited for iterative synthetic sequences in medicinal chemistry and natural product synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: