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CS-W001157 4
Total: USD 88.00

Diphenyl(p-tolyl)methanol

  • CAS No. 5440-76-6

  • Cat. No. CS-0141480
  • Purity≥98%
  • MDL No.MFCD00092323

*For research and further manufacturing use only, not for direct human use.

Diphenyl(p-tolyl)methanol|CS-0141480

Structure of 5440-76-6

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General Information

  • CAS No. 5440-76-6
  • Cat. No. CS-0141480
  • Purity ≥98%
  • MDL No. MFCD00092323
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₁₈O
  • Molecular Weight 274.36
  • Synonym(s) p-Methyltritylcarbinol
  • SMILES OC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=C(C)C=C3

Description

Diphenyl(p-tolyl)methanol offers a stable, bench-ready scaffold for synthetic applications. The aromatic triphenylmethyl-like structure integrates a para-tolyl group, enhancing solubility and stability. This compound serves as a reliable precursor in organic synthesis, particularly in the development of functionalized aryl systems.

Application

Diphenyl(p-tolyl)methanol serves as a stable, bench-ready benzhydryl-type building block for the synthesis of functionalized diarylmethanes. Its tertiary alcohol functionality enables straightforward derivatization via esterification, etherification, or oxidation to the corresponding ketone. The p-tolyl group enhances solubility and provides a handle for further functionalization, while the molecule exhibits excellent stability under standard reaction conditions, facilitating purification and integration into multi-step synthetic sequences.

Synthesis

  • Route1
    • In-stock
      Benzophenone|CS-0015323
      119-61-9
    • null|null
      106-38-7
    • ~85%
    • In-stock
      Diphenyl(p-tolyl)methanol|CS-0141480
      5440-76-6

    References

    • Horn, Markus; Mayr, Herbert Chemistry - A European Journal, 2010 , vol. 16, # 25 p. 7469 - 7477
  • Route2
    • In-stock
      Benzophenone|CS-0015323
      119-61-9
    • null|null
      2417-95-0
    • ~81%
    • In-stock
      Diphenyl(p-tolyl)methanol|CS-0141480
      5440-76-6

    References

    • Seyferth, Dietmar; Hui, Richard C.; Wang, Wei-Liang Journal of Organic Chemistry, 1993 , vol. 58, # 21 p. 5843 - 5845
  • Route3
    • In-stock
      Methyl 4-methylbenzoate|CS-0008417
      99-75-2
    • null|null
      108-86-1
    • ~85%
    • In-stock
      Diphenyl(p-tolyl)methanol|CS-0141480
      5440-76-6

    References

    • Kumar, Sanjeev; Ramachandran, Uma Tetrahedron, 2005 , vol. 61, # 29 p. 7022 - 7028

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   4.27922
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

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