Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

6-Bromopyrazin-2-amine

  • CAS No. 54237-53-5

  • Cat. No. CS-W005068
  • Purity≥95%
  • MDL No.MFCD10697806

*For research and further manufacturing use only, not for direct human use.

6-Bromopyrazin-2-amine|CS-W005068

Structure of 54237-53-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 54237-53-5
  • Cat. No. CS-W005068
  • Purity ≥95%
  • MDL No. MFCD10697806
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄BrN₃
  • Molecular Weight 174.00
  • Synonym(s) 6-Bromopyrazinamine
  • SMILES NC1=NC(=CN=C1)Br

Description

6-Bromopyrazin-2-amine features a bromine substituent at the 6-position and an amino group at the 2-position of the pyrazine ring, enabling diverse cross-coupling transformations. This electron-deficient heterocycle integrates readily into pharmaceutical scaffolds and functional materials, offering high reactivity in palladium-catalyzed processes under standard conditions.

Application

6-Bromopyrazin-2-amine serves as a versatile building block in medicinal chemistry, enabling direct functionalization via palladium-catalyzed cross-coupling reactions. Its bromine substituent facilitates efficient C–C and C–N bond formation under standard Suzuki, Stille, or Buchwald-Hartwig conditions. The pyrazine core provides excellent planarity and nitrogen-rich heterocyclic character, enhancing binding affinity in kinase inhibitors and other bioactive scaffolds. Bench-stable and readily purified by recrystallization, it functions as a reliable intermediate for API development and target-oriented synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   51.8
  • LogP   0.8213
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 6-Bromopyrazin-2-amine sigma6-Bromopyrazin-2-amine manufacturer6-Bromopyrazin-2-amine price6-Bromopyrazin-2-amine structure6-Bromopyrazin-2-amine SDSbuy 6-Bromopyrazin-2-amine6-Bromopyrazin-2-amine supplier6-Bromopyrazin-2-amine uses6-Bromopyrazin-2-amine molecular weightprice of 6-Bromopyrazin-2-amine6-Bromopyrazin-2-amine chemical name formula of 6-Bromopyrazin-2-amine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label