Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2,6-Dimethylisonicotinic acid

  • CAS No. 54221-93-1

  • Cat. No. CS-0007511
  • Purity≥98%
  • MDL No.MFCD03731176

*For research and further manufacturing use only, not for direct human use.

2,6-Dimethylisonicotinic acid|CS-0007511

Structure of 54221-93-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 54221-93-1
  • Cat. No. CS-0007511
  • Purity ≥98%
  • MDL No. MFCD03731176
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₂
  • Molecular Weight 151.16
  • Synonym(s) IFLAB-BB F1371-0184
  • SMILES O=C(C1=CC(C)=NC(C)=C1)O

Description

2,6-Dimethylisonicotinic acid features a pyridine core with methyl groups at the 2 and 6 positions, enhancing steric protection and electronic stability. This configuration imparts improved solubility in organic solvents and resistance to oxidation under standard handling conditions. The carboxylic acid functionality enables direct coupling in peptide synthesis and transition metal catalysis. Its bench-stable nature supports use in iterative reaction sequences without degradation.

Application

2,6-Dimethylisonicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds and bioactive molecules. Its ortho-alkylated pyridine core provides enhanced metabolic stability and modulates electronic properties for targeted ligand design. The carboxylic acid functionality facilitates direct amidation, esterification, or coupling reactions, while the methyl groups offer steric protection and improved solubility. Bench-stable and readily purified by recrystallization, it functions efficiently in standard peptide and macrocyclic coupling protocols.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.39664
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2,6-Dimethylisonicotinic acid sigma2,6-Dimethylisonicotinic acid manufacturer2,6-Dimethylisonicotinic acid price2,6-Dimethylisonicotinic acid structure2,6-Dimethylisonicotinic acid SDSbuy 2,6-Dimethylisonicotinic acid2,6-Dimethylisonicotinic acid supplier2,6-Dimethylisonicotinic acid uses2,6-Dimethylisonicotinic acid molecular weightprice of 2,6-Dimethylisonicotinic acid2,6-Dimethylisonicotinic acid chemical name formula of 2,6-Dimethylisonicotinic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label