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Structure of 5407-98-7
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Cyclobutyl(phenyl)methanone features a rigid cyclobutyl ring fused to a benzophenone scaffold, delivering enhanced metabolic stability and steric bulk. This structural motif integrates readily into bioactive scaffolds, offering improved lipophilicity and conformational restraint for medicinal chemistry applications.
Cyclobutyl(phenyl)methanone serves as a versatile synthetic intermediate for constructing cyclobutane-containing aromatic scaffolds. Its ketone functionality enables standard transformations including nucleophilic addition, reduction to secondary alcohols, and participation in Grignard or organolithium reactions. The molecule exhibits bench stability and facilitates straightforward purification, making it suitable for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: