Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Antimalarial agent 39

  • CAS No. 5407-57-8

  • Cat. No. CS-0197273
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD02179802

*For research and further manufacturing use only, not for direct human use.

Antimalarial agent 39|CS-0197273

Structure of 5407-57-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 5407-57-8
  • Cat. No. CS-0197273
  • Purity ≥97%
  • MDL No. MFCD02179802
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₂ClN₃
  • Molecular Weight None
  • Synonym(s) N1-(7-Chloroquinolin-4-Yl)Ethane-1,2-Diamine
  • SMILES C1=C(C=C2C(=C1)C(=CC=N2)NCCN)Cl

Description

39 delivers potent antimalarial activity through targeted inhibition of Plasmodium falciparum. This compound features a rigid heterocyclic core that enhances membrane penetration and metabolic stability, enabling sustained intracellular concentration. Its electron-deficient aromatic system facilitates selective interaction with key parasite enzymes, minimizing off-target effects in human cells.

Application

Antimalarial agent 39 serves as a validated scaffold in antimalarial drug discovery, enabling efficient synthesis of functionalized quinoline derivatives through well-established coupling and substitution reactions. Its robust bench stability and compatibility with diverse reaction conditions facilitate rapid analog generation for structure-activity relationship studies.

Synthesis

  • Route1
    • In-stock
      4,7-Dichloroquinoline|CS-W020014
      86-98-6
    • null|null
      107-15-3
    • ~97%
    • In-stock
      Antimalarial agent 39|CS-0197273
      5407-57-8

    References

    • Pandey, Shashi; Agarwal, Pooja; Srivastava, Kumkum; RajaKumar; Puri, Sunil K.; Verma, Pravesh; Saxena; Sharma, Abhisheak; Lal, Jawahar; Chauhan, Prem M. S. European Journal of Medicinal Chemistry, 2013 , vol. 66, p. 69 - 81
  • Route2
    • null|null
      849180-03-6
    • ~66%
    • In-stock
      Antimalarial agent 39|CS-0197273
      5407-57-8

    References

    • Solaja, Bogdan A.; Opsenica, Dejan; Smith, Kirsten S.; Milhous, Wilbur K.; Terzic, Natasa; Opsenica, Igor; Burnett, James C.; Nuss, Jon; Gussio, Rick; Bavari, Sina Journal of Medicinal Chemistry, 2008 , vol. 51, # 15 p. 4388 - 4391
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 68, p. 1227

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   50.94
  • LogP   2.2588
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Antimalarial agent 39 sigmaAntimalarial agent 39 manufacturerAntimalarial agent 39 priceAntimalarial agent 39 structureAntimalarial agent 39 SDSbuy Antimalarial agent 39Antimalarial agent 39 supplierAntimalarial agent 39 usesAntimalarial agent 39 molecular weightprice of Antimalarial agent 39Antimalarial agent 39 chemical name formula of Antimalarial agent 39
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label