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Ethyl 5-aminopyrazine-2-carboxylate

  • CAS No. 54013-06-8

  • Cat. No. CS-W006179
  • Purity≥98%
  • MDL No.MFCD08437665

*For research and further manufacturing use only, not for direct human use.

Ethyl 5-aminopyrazine-2-carboxylate|CS-W006179

Structure of 54013-06-8

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General Information

  • CAS No. 54013-06-8
  • Cat. No. CS-W006179
  • Purity ≥98%
  • MDL No. MFCD08437665
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉N₃O₂
  • Molecular Weight 167.17
  • Synonym(s) Ethyl-5-aminopyrazin-2-carboxylat
  • SMILES NC1=CN=C(C=N1)C(=O)OCC

Description

Ethyl 5-aminopyrazine-2-carboxylate features a pyrazine core bearing both amino and carboxylate functionalities, enabling direct incorporation into heterocyclic scaffolds. The ethyl ester group facilitates downstream transformations, while the electron-rich amine enhances reactivity in coupling processes. This compound serves as a key intermediate in medicinal chemistry and agrochemical synthesis.

Application

Ethyl 5-aminopyrazine-2-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrazine-based heterocycles. The amino and ester functionalities offer orthogonal reactivity for coupling, amidation, or cyclization reactions. Its bench-stable nature and compatibility with standard synthetic protocols facilitate straightforward incorporation into API scaffolds and advanced intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   78.1
  • LogP   0.2355
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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