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CS-W001157 4
Total: USD 88.00

Methyl dithiocarbazate

  • CAS No. 5397-03-5

  • Cat. No. CS-0033768
  • Purity≥98%
  • MDL No.MFCD00463356

*For research and further manufacturing use only, not for direct human use.

Methyl dithiocarbazate|CS-0033768

Structure of 5397-03-5

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General Information

  • CAS No. 5397-03-5
  • Cat. No. CS-0033768
  • Purity ≥98%
  • MDL No. MFCD00463356
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂H₆N₂S₂
  • Molecular Weight 122.21
  • Synonym(s) S-Methyldithiocarbazate; SMDTC; NSC 4423
  • SMILES NNC(SC)=S

Description

Hydrazine-S-methylcarbodithioate delivers a reactive thioamide handle for bioconjugation and polymer functionalization. This bench-stable reagent features a nucleophilic hydrazine group paired with an electrophilic dithiocarbamate moiety, enabling selective coupling under mild conditions. Its moisture-tolerant structure simplifies handling in synthetic workflows.

Application

Hydrazine-S-methylcarbodithioate serves as a versatile sulfur-transfer reagent in synthetic organic chemistry, enabling efficient thiation of carbonyl compounds and nucleophilic substrates under mild conditions. Its bench-stable nature and compatibility with diverse functional groups facilitate reliable incorporation into complex molecular architectures. The compound functions effectively in the synthesis of thiocarbonyl-containing intermediates and heterocyclic scaffolds relevant to medicinal chemistry and agrochemical development.

Synthesis

  • Route1
    • null|null
      75-15-0
    • null|null
      74-88-4
    • ~87%
    • In-stock
      Methyl dithiocarbazate|CS-0033768
      5397-03-5

    References

    • Kinfe, Henok H.; Belay, Yonas H. South African Journal of Chemistry, 2013 , vol. 66, p. 130 - 135
  • Route2
    • null|null
      75-15-0
    • null|null
      77-78-1
    • ~77%
    • In-stock
      Methyl dithiocarbazate|CS-0033768
      5397-03-5

    References

    • Wang, Tingting; Miao, Wenke; Wu, Shanshan; Bing, Guifang; Zhang, Xin; Qin, Zhenfang; Yu, Haibo; Qin, Xue; Fang, Jianxin Chinese Journal of Chemistry, 2011 , vol. 29, # 5 p. 959 - 967
  • Route3
    • null|null
      2314-48-9
    • ~90%
    • In-stock
      Methyl dithiocarbazate|CS-0033768
      5397-03-5

    References

    • Shimada, Kazuaki; Otaki, Akihiro; Yanakawa, Masaki; Mabuchi, Shosuke; Yamakado, Naoya; Shimoguchi, Takeshi; Inoue, Kazuya; Kagawa, Takashi; Shoji, Kazutoshi; Takikawa, Yuji Bulletin of the Chemical Society of Japan, 1996 , vol. 69, # 4 p. 1043 - 1054

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   0.0976
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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