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CS-W001157 4
Total: USD 88.00

2-Methoxy-1-naphthaldehyde

  • CAS No. 5392-12-1

  • Cat. No. CS-W016902
  • Purity≥98%
  • MDL No.MFCD00004004

*For research and further manufacturing use only, not for direct human use.

2-Methoxy-1-naphthaldehyde|CS-W016902

Structure of 5392-12-1

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General Information

  • CAS No. 5392-12-1
  • Cat. No. CS-W016902
  • Purity ≥98%
  • MDL No. MFCD00004004
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₀O₂
  • Molecular Weight 186.21
  • Synonym(s) OTAVA-BB BB7020401742
  • SMILES O=CC1=C2C=CC=CC2=CC=C1OC

Description

A calcium indicator; derivative of Fura-2 used to load the chelator into cells

Application

2-Methoxy-1-naphthaldehyde serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of functionalized heterocycles and pharmaceutical intermediates. Its ortho-methoxy substitution enhances electrophilicity at the carbonyl center while improving solubility and stability under standard reaction conditions. The aldehyde group facilitates reliable imine formation, Mannich reactions, and Stetter-type cyclizations, with good tolerance for common functional groups. This compound functions effectively in multi-step syntheses requiring bench-stable, high-purity reagents.

Synthesis

  • Route1
    • 2-Methoxynaphthalene Naproxen Impurity|CS-0229804
      93-04-9
    • null|null
      93-61-8
    • ~70%
    • In-stock
      2-Methoxy-1-naphthaldehyde|CS-W016902
      5392-12-1

    References

    • Matsubara, Hiroshi; Yasuda, Shinji; Sugiyama, Hiroyuki; Ryu, Ilhyong; Fujii, Yasuyuki; Kita, Katsumi Tetrahedron, 2002 , vol. 58, # 20 p. 4071 - 4076
  • Route2
    • 2-Methoxynaphthalene Naproxen Impurity|CS-0229804
      93-04-9
    • null|null
      68-12-2
    • ~85%
    • In-stock
      2-Methoxy-1-naphthaldehyde|CS-W016902
      5392-12-1

    References

    • Shan; Shi; Su Organic Preparations and Procedures International, 2004 , vol. 36, # 4 p. 337 - 340
  • Route3
    • null|null
      56679-89-1
    • ~0%
    • In-stock
      2-Methoxy-1-naphthaldehyde|CS-W016902
      5392-12-1
    • null|null
      80405-32-9

    References

    • Matsumoto, Masakatsu; Kuroda, Keiko; Suzuki, Yoshito Tetrahedron Letters, 1981 , vol. 22, # 34 p. 3253 - 3256

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   2.6609
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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