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CS-W001157 4
Total: USD 88.00

(S)-1-N-Benzyl-prolinol

  • CAS No. 53912-80-4

  • Cat. No. CS-W015842
  • Purity≥97%
  • MDL No.MFCD00011728

*For research and further manufacturing use only, not for direct human use.

(S)-1-N-Benzyl-prolinol|CS-W015842

Structure of 53912-80-4

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General Information

  • CAS No. 53912-80-4
  • Cat. No. CS-W015842
  • Purity ≥97%
  • MDL No. MFCD00011728
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₇NO
  • Molecular Weight 191.27
  • Synonym(s) N-benzyl-L-prolinol
  • SMILES OC[C@H]1N(CC2=CC=CC=C2)CCC1

Description

Precursor in the synthesis of proline-derived homochiral amine oxides. Starting material for enantiomerically pure 3-hydroxypiperidine, a structural feature present in many natural products.

Synthesis

  • Route1
    • Methyl benzyl-D-prolinate|CS-0159374
      113304-84-0
    • ~98%
    • In-stock
      (S)-1-N-Benzyl-prolinol|CS-W015842
      53912-80-4

    References

    • Vargas-Caporali, Jorge; Cruz-Hernandez, Carlos; Juaristi, Eusebio Heterocycles, 2012 , vol. 86, # 2 p. 1275 - 1300
  • Route2

    References

    • Mloston, Grzegorz; Wroblewska, Aneta; Obijalska, Emilia; Heimgartner, Heinz Tetrahedron Asymmetry, 2013 , vol. 24, # 15-16 p. 958 - 965
  • Route3
    • Benzoyl-l-proline|CS-0667985
      5874-58-8
    • ~81%
    • In-stock
      (S)-1-N-Benzyl-prolinol|CS-W015842
      53912-80-4

    References

    • Deur, Christopher J.; Miller, Michael W.; Hegedus, Louis S. Journal of Organic Chemistry, 1996 , vol. 61, # 8 p. 2871 - 2876

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   23.47
  • LogP   1.6433
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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