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CS-W001157 4
Total: USD 88.00

4-Methoxy-2-(trifluoromethyl)aniline

  • CAS No. 53903-49-4

  • Cat. No. CS-0042668
  • Purity≥98%
  • MDL No.MFCD04972660

*For research and further manufacturing use only, not for direct human use.

4-Methoxy-2-(trifluoromethyl)aniline|CS-0042668

Structure of 53903-49-4

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General Information

  • CAS No. 53903-49-4
  • Cat. No. CS-0042668
  • Purity ≥98%
  • MDL No. MFCD04972660
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈F₃NO
  • Molecular Weight 191.15
  • Synonym(s) 2-Amino-5-methoxybenzotrifluoride
  • SMILES FC(F)(F)C1=CC(OC)=CC=C1N

Synthesis

  • Route1
    • 4-Methoxy-1-nitro-2-(trifluoromethyl)benzene|CS-0150503
      344-39-8
    • ~97%
    • In-stock
      4-Methoxy-2-(trifluoromethyl)aniline|CS-0042668
      53903-49-4

    References

    • Monsanto Company Patent: US4879398 A1, 1989 ;
  • Route2
    • In-stock
      1-Trifluoromethyl-1,2-benziodoxol-3(1H)-one|CS-W001669
      887144-94-7
    • null|null
      104-94-9
    • ~57%
    • In-stock
      4-Methoxy-2-(trifluoromethyl)aniline|CS-0042668
      53903-49-4

    References

    • Xie, Jin; Yuan, Xiangai; Abdukader, Ablimit; Zhu, Chengjian; Ma, Jing Organic Letters, 2014 , vol. 16, # 6 p. 1768 - 1771
  • Route3

    References

    • Tetrahedron Letters, , vol. 45, # 26 p. 5131 - 5133

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302+H332-H311-H315-H319-H335-H373
Precautionary Statements : P260-P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P361+P364-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   2.2962
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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