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Structure of 53882-81-8
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3-Oxo-3-(m-tolyl)propanenitrile features a conjugated enone moiety flanked by a nitrile group and a meta-tolyl substituent, enabling efficient integration into heterocyclic synthesis. This electron-deficient system facilitates nucleophilic addition reactions under mild conditions, offering high reactivity in multicomponent couplings and cycloadditions.
3-Oxo-3-(m-tolyl)propanenitrile serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted β-keto nitriles and heterocyclic scaffolds. Its ortho-substituted aryl group enhances steric and electronic control in condensation reactions, while the conjugated enone-nitrile system supports reliable Michael additions and cyclizations. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step synthesis workflows requiring functional group compatibility and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: