Lot numbers can be found on the outside label of a product:
Methyl 5-bromo-4-oxopentanoate
-
CAS No. 53856-93-2
- Cat. No. CS-0042170
- Purity≥96%
- MDL No.MFCD18800850
*For research and further manufacturing use only, not for direct human use.
Structure of 53856-93-2
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 53856-93-2
- Cat. No. CS-0042170
- Purity ≥96%
- MDL No. MFCD18800850
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₆H₉BrO₃
- Molecular Weight 209.04
- Synonym(s) None
- SMILES O=C(OC)CCC(=O)CBr
Description
Methyl 5-bromo-4-oxopentanoate features a bromine atom at the C5 position flanking a ketone group, enabling direct functionalization at the α-carbon. This electrophilic scaffold integrates readily into Michael additions and aldol-type cyclizations, offering a robust entry point for synthesizing substituted cyclopentanones and bioactive heterocycles under mild conditions.
Application
Methyl 5-bromo-4-oxopentanoate serves as a versatile synthon in organic synthesis, enabling efficient construction of substituted γ-keto esters and heterocyclic scaffolds. Its α-bromoketone functionality facilitates nucleophilic substitution and elimination reactions, while the ester group supports further functionalization. The compound exhibits good bench stability and is readily purified by standard techniques, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.
Synthesis
-
Route1
-
In-stock
539-88-8 - ~28%
-
In-stock
53856-93-2
References
-
Array BioPharma Inc. Patent: US2009/156603 A1, 2009 ; Location in patent: Page/Page column 61 ;
-
-
Route2
-
18107-18-1 -
In-stock
1490-25-1 - ~%
-
In-stock
53856-93-2
References
-
SYNGENTA LIMITED; JEANMART, Stephane Andre Marie; LONGSTAFF, Adrian; MATHEWS, Christopher John; RUSSELL, Claire Janet; VINER, Russell Colin; WOOD, Frances Kathryn Patent: WO2011/12862 A1, 2011 ; Location in patent: Page/Page column 89 ;
-
-
Route3
-
67-56-1
-
In-stock
123-76-2 - ~85%
-
In-stock
53856-93-2
References
-
Han, Minsoo; Nam, Kee Dal; Shin, Dongyun; Jeong, Nakcheol; Hahn, Hoh-Gyu Journal of Combinatorial Chemistry, 2010 , vol. 12, # 4 p. 518 - 530
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS05
|
|
Signal Word : Danger
|
UN#: 1759
|
|
Class : 8
|
Packing Group : Ⅱ
|
|
Hazard Statements : H314
|
|
|
Precautionary Statements : P264-P271-P280-P301+P330+P331-P304+P340-P363-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 43.37
- LogP 0.9036
- H_Acceptors 3
- H_Donors 0
- Rotatable_Bonds 4
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Methyl 5-bromo-4-oxopentanoate sigmaMethyl 5-bromo-4-oxopentanoate manufacturerMethyl 5-bromo-4-oxopentanoate priceMethyl 5-bromo-4-oxopentanoate structureMethyl 5-bromo-4-oxopentanoate SDSbuy Methyl 5-bromo-4-oxopentanoateMethyl 5-bromo-4-oxopentanoate supplierMethyl 5-bromo-4-oxopentanoate usesMethyl 5-bromo-4-oxopentanoate molecular weightprice of Methyl 5-bromo-4-oxopentanoateMethyl 5-bromo-4-oxopentanoate chemical name formula of Methyl 5-bromo-4-oxopentanoate