Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-Fluoro-2-nitronaphthalene

  • CAS No. 5385-52-4

  • Cat. No. CS-0128533
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-Fluoro-2-nitronaphthalene|CS-0128533

Structure of 5385-52-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 5385-52-4
  • Cat. No. CS-0128533
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₆FNO₂
  • Molecular Weight 191.16
  • Synonym(s) 1-Fluor-2-nitronaphthalin
  • SMILES O=[N+](C1=CC=C2C=CC=CC2=C1F)[O-]

Description

1-Fluoro-2-nitronaphthalene features a fluorine atom at the 1-position and a nitro group at the 2-position on a naphthalene core, creating a highly electron-deficient aromatic system. This strategic substitution enables efficient coupling in transition-metal-catalyzed reactions, particularly in cross-coupling and nucleophilic aromatic substitution processes. The compound exhibits excellent bench stability and compatibility with standard synthetic protocols, making it a reliable building block for advanced organic synthesis.

Application

1-Fluoro-2-nitronaphthalene serves as a versatile building block in synthetic organic chemistry, enabling regioselective nucleophilic aromatic substitution (SNAr) reactions due to the strong electron-withdrawing effect of the nitro group ortho to fluorine. Its bench-stable nature and compatibility with diverse nucleophiles—such as amines, thiols, and alkoxides—facilitate efficient construction of functionalized naphthalene derivatives. This compound functions as a key intermediate in the synthesis of pharmaceutical scaffolds, agrochemicals, and advanced materials, offering predictable reactivity and straightforward purification.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   43.14
  • LogP   2.8871
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-Fluoro-2-nitronaphthalene sigma1-Fluoro-2-nitronaphthalene manufacturer1-Fluoro-2-nitronaphthalene price1-Fluoro-2-nitronaphthalene structure1-Fluoro-2-nitronaphthalene SDSbuy 1-Fluoro-2-nitronaphthalene1-Fluoro-2-nitronaphthalene supplier1-Fluoro-2-nitronaphthalene uses1-Fluoro-2-nitronaphthalene molecular weightprice of 1-Fluoro-2-nitronaphthalene1-Fluoro-2-nitronaphthalene chemical name formula of 1-Fluoro-2-nitronaphthalene
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label