Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

N-(4-Carboxyphenyl)phthalimide

  • CAS No. 5383-82-4

  • Cat. No. CS-0128346
  • Purity≥97%
  • MDL No.MFCD00023052

*For research and further manufacturing use only, not for direct human use.

N-(4-Carboxyphenyl)phthalimide|CS-0128346

Structure of 5383-82-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 5383-82-4
  • Cat. No. CS-0128346
  • Purity ≥97%
  • MDL No. MFCD00023052
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₉NO₄
  • Molecular Weight 267.24
  • Synonym(s) 4-(1,3-dioxoisoindol-2-yl)benzoic acid
  • SMILES O=C(N1C2=CC=C(C(O)=O)C=C2)C3=CC=CC=C3C1=O

Description

N-(4-Carboxyphenyl)phthalimide features a phthalimide core functionalized with a para-carboxyphenyl group, enabling direct conjugation in bioorthogonal and polymer chemistry. This derivative combines enhanced solubility with robust stability under standard conditions, facilitating efficient coupling reactions without requiring protective groups.

Application

N-(4-Carboxyphenyl)phthalimide serves as a versatile bifunctional building block in synthetic chemistry, enabling efficient conjugation via its carboxylic acid and phthalimide moieties. The carboxylic acid group facilitates amide bond formation under standard coupling conditions, while the phthalimide acts as a stable, removable nitrogen protecting group. This compound exhibits excellent bench stability, predictable reactivity, and compatibility with common purification methods, making it well-suited for peptide synthesis, polymer functionalization, and the construction of heterocyclic scaffolds in medicinal chemistry applications.

Synthesis

  • Route1
    • null|null
      85-44-9
    • 4-Aminobenzoic acid Conivaptan Impurity|CS-0213989
      150-13-0
    • ~89%
    • In-stock
      N-(4-Carboxyphenyl)phthalimide|CS-0128346
      5383-82-4

    References

    • Bhat, Mashooq A.; Al-Omar, Mohammed A. Acta Poloniae Pharmaceutica - Drug Research, 2011 , vol. 68, # 3 p. 375 - 380
  • Route2

    References

    • Pinney, Kevin G.; Katzenellenbogen, John A. Journal of Organic Chemistry, 1991 , vol. 56, # 9 p. 3125 - 3133
  • Route3
    • null|null
      54376-74-8
    • ~%
    • In-stock
      N-(4-Carboxyphenyl)phthalimide|CS-0128346
      5383-82-4

    References

    • Journal of the American Chemical Society, , vol. 71, p. 2933

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   74.68
  • LogP   2.1854
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • N-(4-Carboxyphenyl)phthalimide sigmaN-(4-Carboxyphenyl)phthalimide manufacturerN-(4-Carboxyphenyl)phthalimide priceN-(4-Carboxyphenyl)phthalimide structureN-(4-Carboxyphenyl)phthalimide SDSbuy N-(4-Carboxyphenyl)phthalimideN-(4-Carboxyphenyl)phthalimide supplierN-(4-Carboxyphenyl)phthalimide usesN-(4-Carboxyphenyl)phthalimide molecular weightprice of N-(4-Carboxyphenyl)phthalimideN-(4-Carboxyphenyl)phthalimide chemical name formula of N-(4-Carboxyphenyl)phthalimide
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label