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CS-W001157 4
Total: USD 88.00

4-Methoxybenzamidoxime

  • CAS No. 5373-87-5

  • Cat. No. CS-0647297
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Methoxybenzamidoxime|CS-0647297

Structure of 5373-87-5

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General Information

  • CAS No. 5373-87-5
  • Cat. No. CS-0647297
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₂O₂
  • Molecular Weight 166.18
  • Synonym(s) None
  • SMILES N=C(C1=CC=C(C=C1)OC)NO

Description

4-Methoxybenzamidoxime features a methoxy-substituted aromatic ring paired with a strategically positioned amidoxime group, enabling robust coordination in metal chelation and serving as a key intermediate in heterocyclic synthesis.

Application

4-Methoxybenzamidoxime serves as a versatile building block in heterocyclic synthesis, enabling efficient access to oxazole and oxadiazole scaffolds through standard cyclization protocols. Its amide and amidoxime functionalities exhibit robust bench stability and tolerate common reaction conditions, facilitating straightforward purification and integration into medicinal chemistry campaigns. The methoxy group enhances solubility and provides a handle for further derivatization.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   65.34
  • LogP   0.99937
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

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