Lot numbers can be found on the outside label of a product:
5-Amino-1-methyl-1H-pyrazole-4-carbonitrile
-
CAS No. 5334-41-8
- Cat. No. CS-W002376
- Purity≥98%
- MDL No.MFCD00114569
*For research and further manufacturing use only, not for direct human use.
Structure of 5334-41-8
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 5334-41-8
- Cat. No. CS-W002376
- Purity ≥98%
- MDL No. MFCD00114569
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₅H₆N₄
- Molecular Weight 122.13
- Synonym(s) 4-(acetylamino)-N-(propan-2-yl)benzamide
- SMILES CN1C(N)=C(C=N1)C#N
Description
5-Amino-1-methyl-1H-pyrazole-4-carbonitrile features a pyrazole core functionalized with an amino group at C5, a methyl substituent at N1, and a nitrile at C4. This arrangement imparts enhanced solubility and stability under standard conditions, enabling direct integration into heterocyclic synthesis. The electron-rich amine and conjugated nitrile facilitate coupling reactions, making it a valuable scaffold for medicinal chemistry and materials development.
Application
5-Amino-1-methyl-1H-pyrazole-4-carbonitrile serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to pyrazole-based scaffolds. Its dual functionality—amino and nitrile groups—facilitates diverse downstream transformations, including amidation, cyclization, and metal-catalyzed coupling reactions. The compound exhibits good bench stability and is readily purified by recrystallization, supporting its use in multi-step synthesis and API development workflows.
Synthesis
-
Route1
-
302-15-8 -
123-06-8 - ~79%
-
In-stock
5334-41-8
References
-
RALLIS INDIA LIMITED; PALIMKAR, Sanjay Sambhajirao; PAWAR, Jivan Dhanraj; SANKAR, B; KADAM, Subhash Rajaram; HINDUPUR, Rama Mohan; PRABHU, Venkatesh M.; PATI, Hari Narayan; SUPHALA, Vadiraj Gopinath; MANE, Avinash Sheshrao Patent: WO2014/2111 A1, 2014 ; Location in patent: Page/Page column 38 ;
-
-
Route2
-
60-34-4
-
123-06-8
- ~78%
-
In-stock
5334-41-8
References
-
Harden; Quinn; Scammells Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2892 - 2898 Title/Abstract Full Text View citing articles Show Details Dooley, Michael J.; Quinn, Ronald J.; Scammells, Peter J. Australian Journal of Chemistry, 1989 , vol. 42, # 5 p. 747 - 750
-
-
Route3
-
111267-92-6
- ~47%
-
In-stock
5334-41-8
-
111267-93-7
References
-
Journal of Organic Chemistry, , vol. 53, # 2 p. 382 - 386
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS06
|
|
Signal Word : Danger
|
UN#: 2811
|
|
Class : 6.1
|
Packing Group : Ⅲ
|
|
Hazard Statements : H301-H311-H331
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 67.63
- LogP -0.12602
- H_Acceptors 4
- H_Donors 1
- Rotatable_Bonds 0
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 5334-41-8 sigma5334-41-8 manufacturer5334-41-8 price5334-41-8 structure5334-41-8 SDSbuy 5334-41-85334-41-8 supplier5334-41-8 uses5334-41-8 molecular weightprice of 5334-41-85334-41-8 chemical name formula of 5334-41-8