Dipropylamine hydrochloride

Name: Dipropylamine hydrochloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 5326-84-1
Cat. No. CS-0187381
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 5326-84-1

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General Information

CAS No. 5326-84-1
Cat. No. CS-0187381
Purity ≥98%
MDL No. None
Storage Store at room temperature, keep dry and cool
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₆ClN
Molecular Weight 137.65
Synonym(s) N,N-Dipropylamine hydrochloride
SMILES CCCNCCC.Cl

Description

Dipropylamine hydrochloride is a bench-stable, moisture-tolerant amine salt featuring two propyl chains that enhance solubility in polar solvents. This compound serves as a versatile synthetic intermediate in pharmaceutical and agrochemical synthesis, enabling efficient deprotonation and nucleophilic substitution under standard conditions.

Application

Dipropylamine hydrochloride serves as a stable, bench-ready amine source for nucleophilic substitutions and reductive amination protocols. Its tertiary amine functionality enables efficient salt formation and facilitates purification via crystallization or acid-base extraction. Widely used in the synthesis of pharmaceutical intermediates and agrochemicals, it functions reliably in standard organic transformations with good functional group tolerance and predictable reactivity.

Synthesis

Route1
- In-stock
  
  3599-89-1
- ~18%
- In-stock
  
  5326-84-1
References
- Okamoto, Yoshihisa; Kinoshita, Toshio Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 4 p. 1165 - 1169
Route2
- 64-17-5
- 2315-37-9
- 17356-08-0
- ~%
- In-stock
  
  5326-84-1
- In-stock
  
  556-90-1
References
- Speziale; Hamm Journal of the American Chemical Society, 1956 , vol. 78, p. 5580,5582

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

TPSA 12.03
LogP 1.8178
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 4

Other Classifications

Building Blocks Functional Group Amine

Key Words

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Dipropylamine hydrochloride

CAS No. 5326-84-1

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