2-Amino-5-iodobenzoic acid

Name: 2-Amino-5-iodobenzoic acid
Brand: ChemScene
Availability: InStock
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CAS No. 5326-47-6
Cat. No. CS-W002034
Purity≥95%
MDL No.MFCD00007849

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 5326-47-6

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Description

2-Amino-5-iodobenzoic acid features a strategically positioned iodine atom and amino group on the aromatic ring, enabling direct functionalization in cross-coupling reactions. This bench-stable derivative integrates readily into bioconjugation workflows and serves as a key scaffold for developing targeted pharmaceutical intermediates and imaging agents.

Application

2-Amino-5-iodobenzoic acid serves as a versatile building block for the synthesis of biologically active heterocycles and pharmaceutical intermediates. The ortho-amino and iodo substituents enable sequential cross-coupling and cyclization reactions under standard palladium-catalyzed conditions. Its bench-stable crystalline form facilitates handling and purification, while the carboxylic acid group supports direct derivatization or salt formation for improved solubility in synthetic workflows.

General Information

CAS No. 5326-47-6
Cat. No. CS-W002034
Purity ≥95%
MDL No. MFCD00007849
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆INO₂
Molecular Weight 263.03
Synonym(s) 5-Iodoanthranilic Acid
SMILES Ic1ccc(c(c1)C(=O)O)N

Computational Chemistry Data

TPSA 63.32
LogP 1.5716
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352

Quality Control

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Other Classifications

Building Blocks Functional Group Iodide

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Unnatural Amino Acid Derivatives

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2-Amino-5-iodobenzoic acid

CAS No. 5326-47-6

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