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CS-W001157 4
Total: USD 88.00

4-(4-Sulfophenyl)benzenesulfonic acid

  • CAS No. 5314-37-4

  • Cat. No. CS-0035490
  • Purity≥97%
  • MDL No.MFCD00035762

*For research and further manufacturing use only, not for direct human use.

4-(4-Sulfophenyl)benzenesulfonic acid|CS-0035490

Structure of 5314-37-4

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General Information

  • CAS No. 5314-37-4
  • Cat. No. CS-0035490
  • Purity ≥97%
  • MDL No. MFCD00035762
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₀O₆S₂
  • Molecular Weight 314.33
  • Synonym(s) Biphenyl-4,4'-disulphonic acid
  • SMILES O=S(=O)(O)C1=CC=C(C=C1)C=2C=CC(=CC2)S(=O)(=O)O

Description

1-Methylisatin is used as a reactant for stereoselective preparation of spirobicyclic and bis-spirotricyclic pyrazolidinones, for regioselective preparation of spirocyclic oxindole-butenolides, for synthesis of spiro-oxindoles, for preparation of unsymmetrical oxindoles, for stereoselective preparation of hydroxyloxindoles via Morita-Baylis-Hillman reaction, for preparation of pyridinecarboxylic acid [(oxo)indolylidene)hydrazide derivatives (Schiff base hydrazides) as antibacterial agents.

Application

4-(4-Sulfophenyl)benzenesulfonic acid serves as a robust, water-soluble building block for constructing sulfonated aromatic systems. Its dual sulfonic acid groups enable strong ionic interactions and enhance solubility in polar media, facilitating purification and handling. The molecule functions effectively in coupling reactions, particularly in the synthesis of functional dyes, surfactants, and ion-exchange materials. Bench-stable and compatible with standard synthetic protocols, it offers reliable performance in scale-up applications.

Synthesis

  • Route1

    References

    • Muesmann, Thomas W.T.; Wickleder, Mathias S.; Christoffers, Jens Synthesis, 2011 , # 17 art. no. T48511SS, p. 2775 - 2780
  • Route2
    • null|null
      92-52-4
    • ~%
    • In-stock
      4-(4-Sulfophenyl)benzenesulfonic acid|CS-0035490
      5314-37-4

    References

    • Helvetica Chimica Acta, , vol. 14, p. 751,775
  • Route3

    References

    • Synthesis, , # 17 art. no. T48511SS, p. 2775 - 2780

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314-H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   108.74
  • LogP   1.847
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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