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Structure of 53088-68-9
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Methyl 2-(3-chlorophenyl)acetate is a chlorinated aromatic ester featuring a benzylic ester linkage. This compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, offering enhanced reactivity at the carbonyl center due to the electron-withdrawing chlorine substituent. The para-chloro group stabilizes adjacent carbanions and facilitates selective functionalization under mild conditions.
Methyl 2-(3-chlorophenyl)acetate serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling efficient access to biologically relevant arylacetic acid derivatives. Its stability under standard reaction conditions and compatibility with diverse transformations—such as nucleophilic substitutions, reductions, and coupling reactions—facilitates straightforward functionalization of the aromatic ring and side-chain manipulation. The methyl ester group allows for selective derivatization, while the 3-chloro substituent provides a handle for further electrophilic or cross-coupling modifications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: