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CS-W001157 4
Total: USD 88.00

1-(Benzyloxy)-3-bromobenzene

  • CAS No. 53087-13-1

  • Cat. No. CS-W004106
  • Purity≥98%
  • MDL No.MFCD00155065

*For research and further manufacturing use only, not for direct human use.

1-(Benzyloxy)-3-bromobenzene|CS-W004106

Structure of 53087-13-1

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General Information

  • CAS No. 53087-13-1
  • Cat. No. CS-W004106
  • Purity ≥98%
  • MDL No. MFCD00155065
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₁BrO
  • Molecular Weight 263.13
  • Synonym(s) Benzyl 3-Bromophenyl Ether
  • SMILES Brc1cccc(c1)OCc1ccccc1

Description

Potent inhibitor of serine/threonine-specific protein phosphatases 1 and 2A (PP1 and PP2A). Does not inhibit tyrosine or alkaline phosphatases

Application

1-(Benzyloxy)-3-bromobenzene serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable aryl bromide functionality. The benzyloxy group provides orthogonal protection for phenolic hydroxyls and enhances solubility during synthesis. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient construction of complex aromatic architectures, including substituted biaryls and heterocyclic scaffolds relevant to medicinal chemistry.

Synthesis

  • Route1
    • null|null
      591-20-8
    • null|null
      100-44-7
    • ~92%
    • In-stock
      1-(Benzyloxy)-3-bromobenzene|CS-W004106
      53087-13-1

    References

    • Fergusson, Kenneth M.; Hird, Michael Journal of Materials Chemistry, 2010 , vol. 20, # 15 p. 3069 - 3078
  • Route2
    • null|null
      591-20-8
    • null|null
      100-39-0
    • ~99%
    • In-stock
      1-(Benzyloxy)-3-bromobenzene|CS-W004106
      53087-13-1

    References

    • Kim, Jeongryul; Kim, Young Kook; Park, Nokyoung; Hahn, Jong Hoon; Ahn, Kyo Han Journal of Organic Chemistry, 2005 , vol. 70, # 18 p. 7087 - 7092
  • Route3
    • null|null
      585-79-5
    • In-stock
      Benzyl alcohol|CS-4355
      100-51-6
    • ~95%
    • In-stock
      1-(Benzyloxy)-3-bromobenzene|CS-W004106
      53087-13-1

    References

    • Effenberger, Franz; Koch, Markus; Streicher, Willi Chemische Berichte, 1991 , vol. 124, # 1 p. 163 - 173

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H413
Precautionary Statements : P264-P270-P273-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   4.0281
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   3

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