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CS-W001157 4
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1-(5-Methylpyridin-2-yl)ethanone

  • CAS No. 5308-63-4

  • Cat. No. CS-0005383
  • Purity≥97%
  • MDL No.MFCD06658292

*For research and further manufacturing use only, not for direct human use.

1-(5-Methylpyridin-2-yl)ethanone|CS-0005383

Structure of 5308-63-4

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General Information

  • CAS No. 5308-63-4
  • Cat. No. CS-0005383
  • Purity ≥97%
  • MDL No. MFCD06658292
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO
  • Molecular Weight 135.16
  • Synonym(s) 2-Acetyl-5-methylpyridine
  • SMILES O=C(C)C(C=C1)=NC=C1C

Description

1-(5-Methylpyridin-2-yl)ethanone features a pyridine ring bearing a methyl group at the 5-position and an acetyl substituent at the 2-position, delivering a sterically accessible, electron-deficient heterocyclic scaffold. This configuration enables direct incorporation into pharmaceutical intermediates and ligand frameworks, offering enhanced solubility in polar organic solvents and stability under standard bench conditions.

Application

1-(5-Methylpyridin-2-yl)ethanone serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-containing scaffolds via standard functional group interconversions. Its stability under routine reaction conditions and compatibility with common coupling protocols facilitate straightforward integration into complex molecular architectures. The ketone functionality reacts selectively with nucleophiles and participates in transition-metal-catalyzed transformations, making it valuable for constructing bioactive heterocycles and API intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   1.59262
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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