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CS-W001157 4
Total: USD 88.00

1H-Inden-1-one, 4,7-dichloro-2,3-dihydro-

  • CAS No. 52977-63-6

  • Cat. No. CS-0030410
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1H-Inden-1-one, 4,7-dichloro-2,3-dihydro-|CS-0030410

Structure of 52977-63-6

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General Information

  • CAS No. 52977-63-6
  • Cat. No. CS-0030410
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆Cl₂O
  • Molecular Weight 201.05
  • Synonym(s) 4,7-Dichloro-1-indanone
  • SMILES O=C1CCC2=C1C(Cl)=CC=C2Cl

Description

4,7-Dichloro-2,3-dihydro-1H-inden-1-one is a chlorinated indenone derivative featuring two chlorine atoms at the 4 and 7 positions, conferring enhanced electron-withdrawing character. This sterically accessible scaffold serves as a key building block in synthetic routes to functionalized heterocycles and bioactive molecules. The compound exhibits bench-stable handling under standard conditions and integrates readily into transition metal-catalyzed coupling processes.

Application

4,7-Dichloro-2,3-dihydro-1H-inden-1-one serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of substituted indene scaffolds. Its dichloro substitution pattern enhances electrophilic reactivity at the carbonyl-adjacent positions, facilitating nucleophilic additions and transition-metal-catalyzed couplings. The compound exhibits good bench stability and compatibility with standard purification methods, making it well-suited for use in medicinal chemistry campaigns and API intermediate synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   3.1223
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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