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CS-W001157 4
Total: USD 88.00

2-Aminobenzaldehyde

  • CAS No. 529-23-7

  • Cat. No. CS-W007486
  • Purity≥96%
  • MDL No.MFCD00007709

*For research and further manufacturing use only, not for direct human use.

2-Aminobenzaldehyde|CS-W007486

Structure of 529-23-7

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General Information

  • CAS No. 529-23-7
  • Cat. No. CS-W007486
  • Purity ≥96%
  • MDL No. MFCD00007709
  • Storage -20°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇NO
  • Molecular Weight 121.14
  • Synonym(s) o-Amino Benzaldehyde
  • SMILES NC1=C(C=O)C=CC=C1

Application

2-Aminobenzaldehyde serves as a versatile building block in heterocyclic synthesis, enabling efficient access to quinoline and isoquinoline scaffolds via condensation and cyclization protocols. Its ortho-amino and aldehyde functionalities exhibit complementary reactivity, facilitating one-pot transformations with amines, hydrazines, or nucleophiles under mild conditions. Bench-stable and readily purified by recrystallization, it functions reliably in medicinal chemistry campaigns and catalyst ligand development.

Synthesis

  • Route1

    References

    • WO2009/66072 A2, ; Page/Page column 56; 58 ; WO 2009/066072 A2
  • Route2

    References

    • Angewandte Chemie - International Edition, , vol. 44, # 22 p. 3423 - 3426
  • Route3

    References

    • Bioorganic and Medicinal Chemistry, , vol. 22, # 8 p. 2447 - 2460

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.09
  • LogP   1.0813
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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