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CS-W001157 4
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Sarcosine ethyl ester hydrochloride

  • CAS No. 52605-49-9

  • Cat. No. CS-W020595
  • Purity≥97%
  • MDL No.MFCD00012506

*For research and further manufacturing use only, not for direct human use.

Sarcosine ethyl ester hydrochloride|CS-W020595

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General Information

  • CAS No. 52605-49-9
  • Cat. No. CS-W020595
  • Purity ≥97%
  • MDL No. MFCD00012506
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂ClNO₂
  • Molecular Weight 153.61
  • Synonym(s) N-[(Ethoxycarbonyl)methyl]-N-methylamine hydrochloride; Sacrosine ethyl ester hydrochloride
  • SMILES O=C(OCC)CNC.[H]Cl

Description

Sarcosine ethyl ester hydrochloride features a stable, bench-ready zwitterionic form that facilitates direct incorporation into peptide synthesis workflows. The ethyl ester moiety enables efficient coupling under standard conditions, while the hydrochloride salt enhances solubility and handling in aqueous or polar organic media. This derivative serves as a key building block for bioactive peptides and analogs requiring N-methylated glycine units.

Application

Sarcosine ethyl ester hydrochloride serves as a versatile building block in peptide synthesis and medicinal chemistry, offering a stable, bench-ready source of the N-methylglycine moiety. Its zwitterionic character enhances solubility and handling, while the protected amine facilitates selective coupling reactions. The hydrochloride salt improves crystallinity and storage stability, enabling reliable use in multi-step syntheses of bioactive peptides and heterocyclic scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   0.1907
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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