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Structure of 52415-00-6
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4-Iodo-2-methyl-1-nitrobenzene features a nitro group at the para position relative to iodine, creating a strongly electron-deficient aromatic system ideal for palladium-catalyzed cross-coupling reactions. The methyl substituent enhances regioselectivity in subsequent functionalization steps. This bench-stable compound integrates readily into complex molecular architectures under standard conditions.
4-Iodo-2-methyl-1-nitrobenzene serves as a versatile building block in cross-coupling chemistry, enabling efficient Suzuki and Stille reactions due to the ortho-methyl group’s steric and electronic influence. The iodide functionality provides high reactivity under mild conditions, while the nitro group offers stability and compatibility with standard synthetic workflows. Its bench-stable nature and predictable regioselectivity facilitate reliable construction of substituted aromatic scaffolds for medicinal chemistry and materials applications.
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: