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Structure of 5217-05-0
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1-Methylcyclopentane-1-carboxylic acid features a rigid cyclopentane core with a carboxylic acid group at the quaternary carbon, delivering enhanced steric and electronic stability. This structural motif enables direct incorporation into bioactive scaffolds and serves as a robust building block for medicinal chemistry campaigns requiring constrained, lipophilic motifs under standard conditions.
1-Methylcyclopentane-1-carboxylic acid serves as a versatile building block in medicinal and synthetic chemistry, offering a rigid, sterically defined cyclopentane scaffold with a carboxylic acid functional group. Its bench-stable nature and compatibility with standard coupling reactions enable efficient incorporation into peptide mimetics, macrocyclic compounds, and bioactive molecule frameworks. The α-methyl substitution enhances metabolic stability and modulates lipophilicity, making it valuable for structure–activity optimization in drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: