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Structure of 52147-97-4
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(E)-2-Phenylethylenesulfonyl chloride features a conjugated vinyl sulfone moiety enabling direct incorporation into Michael acceptor-based synthetic sequences. The sulfonyl chloride group provides high reactivity toward nucleophiles, facilitating rapid functionalization under mild conditions. This compound serves as a stable, bench-ready electrophile for constructing complex organic architectures in medicinal chemistry and materials synthesis.
(E)-2-Phenylethylenesulfonyl chloride serves as a versatile electrophilic sulfonylating agent, enabling efficient introduction of sulfonate groups under mild conditions. Its conjugated vinyl sulfone structure enhances stability and facilitates selective reactions with nucleophiles such as amines and thiols, making it valuable for synthesizing sulfonamide and sulfonate derivatives in medicinal chemistry workflows. The compound exhibits good bench stability and is compatible with common functional groups, supporting straightforward purification and integration into multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314-H318
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: