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CS-W001157 4
Total: USD 88.00

6-Methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol

  • CAS No. 5196-20-3

  • Cat. No. CS-0437368
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol|CS-0437368

Structure of 5196-20-3

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General Information

  • CAS No. 5196-20-3
  • Cat. No. CS-0437368
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₂
  • Molecular Weight 151.16
  • Synonym(s) Vitamin B6 Impurity 1 ( Vitamin B6 EP Impurity A
  • SMILES OC1=C(COC2)C2=CN=C1C

Description

Tween 60 for synthesis. CAS 9005-67-8, pH 5.5 - 7.7 (50 g/l, HO, 25 C).

Application

6-Methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol serves as a versatile heterocyclic building block for medicinal chemistry applications, offering a rigid, oxygenated scaffold with defined regiochemistry. The molecule exhibits bench stability and facilitates downstream functionalization via electrophilic substitution or coupling reactions. Its fused furan-pyridine core provides favorable pharmacophoric properties, while the phenolic hydroxyl group enables derivatization for solubility modulation or target engagement.

Synthesis

  • Route1
    • Propargyl Ether|CS-0622506
      6921-27-3
    • ~%
    • In-stock
      6-Methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol|CS-0437368
      5196-20-3

    References

    • Geiger; Lalonde; Stoller; Schleich Helvetica Chimica Acta, 1984 , vol. 67, # 5 p. 1274 - 1282
  • Route2
    • null|null
      856412-06-1
    • ~%
    • In-stock
      6-Methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol|CS-0437368
      5196-20-3

    References

    • Gutnov, Andrey; Abaev, Vladimir; Redkin, Dmitry; Fischer, Christine; Bonrath, Werner; Heller, Barbara Synlett, 2005 , # 7 art. no. G48004ST, p. 1188 - 1190
  • Route3
    • null|null
      856412-04-9
    • ~%
    • In-stock
      6-Methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol|CS-0437368
      5196-20-3

    References

    • Gutnov, Andrey; Abaev, Vladimir; Redkin, Dmitry; Fischer, Christine; Bonrath, Werner; Heller, Barbara Synlett, 2005 , # 7 art. no. G48004ST, p. 1188 - 1190

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   42.35
  • LogP   1.12582
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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