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Structure of 518987-33-2
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6-Fluoro-1H-indazole-3-carbaldehyde features a fluorinated indazole core paired with an aldehyde handle, enabling direct integration into bioconjugation and medicinal chemistry campaigns. The electron-deficient aromatic system enhances reactivity in nucleophilic additions, while the bench-stable aldehyde group supports reliable coupling under standard conditions.
6-Fluoro-1H-indazole-3-carbaldehyde serves as a versatile building block for the synthesis of bioactive heterocycles, leveraging its orthogonal reactivity at the aldehyde and fluorinated indazole core. The aldehyde group facilitates efficient coupling reactions, including Wittig, reductive amination, and Grignard additions, while the 6-fluorine substituent enables subsequent palladium-catalyzed cross-coupling or nucleophilic substitution. Its bench-stable nature and compatibility with diverse functional groups make it well-suited for medicinal chemistry campaigns and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: