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CS-W001157 4
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5-Bromopentan-1-amine hydrobromide

  • CAS No. 51874-27-2

  • Cat. No. CS-0006784
  • Purity≥96%
  • MDL No.MFCD17012761

*For research and further manufacturing use only, not for direct human use.

5-Bromopentan-1-amine hydrobromide|CS-0006784

Structure of 51874-27-2

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General Information

  • CAS No. 51874-27-2
  • Cat. No. CS-0006784
  • Purity ≥96%
  • MDL No. MFCD17012761
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₃Br₂N
  • Molecular Weight 246.97
  • Synonym(s) None
  • SMILES BrCCCCCN.Br

Description

5-Bromopentan-1-amine hydrobromide delivers a bromoalkyl chain tethered to a primary amine, enabling direct incorporation into functionalized polymers and bioconjugates. The hydrobromide salt enhances solubility in aqueous and polar organic media while maintaining stability under standard handling conditions. This bifunctional scaffold facilitates efficient coupling reactions in synthetic and medicinal chemistry workflows.

Application

5-Bromopentan-1-amine hydrobromide serves as a versatile bifunctional building block for the synthesis of bioactive heterocycles and peptide derivatives. The primary amine and bromide functionalities enable straightforward alkylation, amidation, and transition-metal-catalyzed coupling reactions. Its bench-stable solid form facilitates handling and purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

Synthesis

  • Route1

    References

    • Manzo, Emiliano; Pagano, Dario; Carbone, Marianna; Ciavatta, M. Letizia; Gavagnin, Margherita Arkivoc, 2012 , vol. 2012, # 9 p. 220 - 228

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.0882
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   4

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