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Structure of 51843-24-4
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1-(5-Chloro-1H-indol-3-yl)ethanone features a chlorinated indole core linked to an acetyl group, enabling direct incorporation into bioactive molecule scaffolds. This electron-deficient ketone serves as a key intermediate in medicinal chemistry, particularly for targeting indole-based pharmacophores. The compound exhibits stability under standard handling conditions and facilitates efficient derivatization via nucleophilic addition or enolate formation.
1-(5-Chloro-1H-indol-3-yl)ethanone serves as a versatile building block for indole-based pharmaceutical intermediates. The ketone functionality enables direct nucleophilic addition, reductive amination, and condensation reactions, facilitating access to diverse heterocyclic scaffolds. Bench-stable and readily purified by recrystallization, it exhibits good functional group tolerance in standard synthetic workflows, making it well-suited for medicinal chemistry campaigns targeting CNS agents and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: