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Structure of 51516-70-2
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5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carbonitrile features a conjugated pyrazole core bearing an electron-rich amino group and a strongly electron-withdrawing nitrile, flanked by a 4-fluorophenyl substituent. This combination imparts enhanced solubility and reactivity in transition metal-catalyzed coupling processes. The molecule exhibits bench-stable handling characteristics under standard conditions.
5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carbonitrile serves as a versatile building block in medicinal chemistry, enabling rapid access to functionalized pyrazole scaffolds. The amino and nitrile groups facilitate diverse downstream transformations, including amidation, cyclization, and coupling reactions. Its bench-stable nature and compatibility with standard synthetic protocols make it well-suited for parallel library synthesis and API intermediate development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: