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Structure of 51446-30-1
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This fluorinated benzoic acid derivative integrates a hydroxyl group at the para position relative to the carboxylate, enabling versatile conjugation and enhanced solubility. The electron-withdrawing fluorine substituent modulates reactivity and stability, making it suitable for synthetic intermediates in pharmaceutical and agrochemical development under standard conditions.
2-Fluoro-5-hydroxybenzoic acid serves as a versatile building block for bioactive molecule synthesis, enabling direct incorporation of fluorinated aromatic cores with orthogonal hydroxyl and carboxylic acid functionalities. Its bench-stable nature facilitates straightforward derivatization via esterification, amidation, or Suzuki coupling, while the ortho-fluoro group supports nucleophilic aromatic substitution under mild conditions. The compound functions effectively in the construction of heterocyclic scaffolds and drug-like intermediates requiring precise regiochemistry and functional group compatibility.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: