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CS-W001157 4
Total: USD 88.00

(4-(Aminomethyl)phenyl)boronic acid

  • CAS No. 51239-46-4

  • Cat. No. CS-0096263
  • Purity≥97%
  • MDL No.MFCD06213214

*For research and further manufacturing use only, not for direct human use.

(4-(Aminomethyl)phenyl)boronic acid|CS-0096263

Structure of 51239-46-4

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General Information

  • CAS No. 51239-46-4
  • Cat. No. CS-0096263
  • Purity ≥97%
  • MDL No. MFCD06213214
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀BNO₂
  • Molecular Weight 150.97
  • Synonym(s) 4-Boronobenzylamine
  • SMILES OB(C1=CC=C(CN)C=C1)O

Description

This boronate moiety integrates a para-aminomethyl group, enabling direct conjugation to biomolecules via amine-reactive chemistries. The pendant primary amine facilitates site-specific labeling and bioconjugation, while the boronic acid offers stable binding to diols in glycoconjugates. Bench-stable under standard conditions, this reagent streamlines synthesis of targeted probes for chemical biology applications.

Application

(4-(Aminomethyl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The pendant primary amine facilitates downstream derivatization and orthogonal functional group manipulation, while the boronic acid moiety offers excellent bench stability and compatibility with diverse reaction partners. Its utility is well-established in medicinal chemistry and materials science for constructing complex aromatic architectures with precise structural control.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   66.48
  • LogP   -1.1749
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

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