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Structure of 51173-05-8
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5-Fluoro-2-hydroxypyridine features a strategically positioned fluorine atom and a hydroxyl group on the pyridine scaffold, enabling enhanced reactivity in nucleophilic substitution and metal-catalyzed coupling processes. This electron-deficient heterocycle serves as a key building block for bioactive compounds and functional materials.
5-Fluoro-2-hydroxypyridine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C2 position via nucleophilic substitution or transition-metal-catalyzed coupling. Its hydroxyl group offers orthogonal reactivity for derivatization, while the fluorine substituent enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and facilitates efficient synthesis of pyridine-based scaffolds relevant to API development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: