Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3,6-Dichloropyridazine-4-carboxylic acid

  • CAS No. 51149-08-7

  • Cat. No. CS-W001153
  • Purity≥95%
  • MDL No.MFCD00011575

*For research and further manufacturing use only, not for direct human use.

3,6-Dichloropyridazine-4-carboxylic acid|CS-W001153

Structure of 51149-08-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 51149-08-7
  • Cat. No. CS-W001153
  • Purity ≥95%
  • MDL No. MFCD00011575
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₂Cl₂N₂O₂
  • Molecular Weight 192.99
  • Synonym(s) 4-Carboxy-3,6-dichloropyridazine
  • SMILES O=C(C1=CC(Cl)=NN=C1Cl)O

Application

3,6-Dichloropyridazine-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridazinone-based scaffolds through nucleophilic substitution and subsequent derivatization. Its dual chloro groups at C3 and C6 exhibit high reactivity toward amines, alcohols, and thiols under mild conditions, facilitating the construction of diverse heterocyclic architectures. The carboxylic acid functionality allows for direct coupling reactions or salt formation, enhancing solubility and purification. Bench-stable and readily handled, it functions effectively in multi-step synthesis workflows requiring functional group compatibility and predictable transformation profiles.

Synthesis

  • Route1

    References

    • Liscio, Paride; Carotti, Andrea; Asciutti, Stefania; Karlberg, Tobias; Bellocchi, Daniele; Llacuna, Laura; Macchiarulo, Antonio; Aaronson, Stuart A; Schueler, Herwig; Pellicciari, Roberto; Camaioni, Emidio Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2807 - 2812
  • Route2

    References

    • ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2004/108707 A1, 2004 ; Location in patent: Page 53 ; WO 2004/108707 A1
  • Route3

    References

    • Liscio, Paride; Carotti, Andrea; Asciutti, Stefania; Karlberg, Tobias; Bellocchi, Daniele; Llacuna, Laura; Macchiarulo, Antonio; Aaronson, Stuart A; Schueler, Herwig; Pellicciari, Roberto; Camaioni, Emidio Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2807 - 2812

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   63.08
  • LogP   1.4816
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3,6-Dichloropyridazine-4-carboxylic acid sigma3,6-Dichloropyridazine-4-carboxylic acid manufacturer3,6-Dichloropyridazine-4-carboxylic acid price3,6-Dichloropyridazine-4-carboxylic acid structure3,6-Dichloropyridazine-4-carboxylic acid SDSbuy 3,6-Dichloropyridazine-4-carboxylic acid3,6-Dichloropyridazine-4-carboxylic acid supplier3,6-Dichloropyridazine-4-carboxylic acid uses3,6-Dichloropyridazine-4-carboxylic acid molecular weightprice of 3,6-Dichloropyridazine-4-carboxylic acid3,6-Dichloropyridazine-4-carboxylic acid chemical name formula of 3,6-Dichloropyridazine-4-carboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label