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Structure of 51035-40-6
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4-(Pyridin-2-yl)phenol integrates a pyridine ring with a phenolic hydroxyl group, enabling dual coordination sites for metal complexation. This structural motif enhances chelation capacity in catalytic systems and provides a rigid, electron-rich scaffold for ligand design in transition metal chemistry.
4-(Pyridin-2-yl)phenol serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its pyridine and phenolic functionalities offer orthogonal reactivity for metal-catalyzed cross-couplings, electrophilic substitutions, and derivatization. The compound exhibits good bench stability, moderate solubility in common organic solvents, and facilitates purification via crystallization or chromatography, making it well-suited for scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: