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CS-W001157 4
Total: USD 88.00

Cystamine

  • CAS No. 51-85-4

  • Cat. No. CS-0086613
  • Purity≥95%
  • MDL No.MFCD01002952

*For research and further manufacturing use only, not for direct human use.

Cystamine|CS-0086613

Structure of 51-85-4

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General Information

  • CAS No. 51-85-4
  • Cat. No. CS-0086613
  • Purity ≥95%
  • MDL No. MFCD01002952
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₂N₂S₂
  • Molecular Weight 152.28
  • Synonym(s) None
  • SMILES NCCSSCCN

Description

Cystamine delivers a bifunctional thiol handle ideal for bioconjugation and surface functionalization. This bench-stable compound features a disulfide-linked dithiol structure that enables site-specific coupling under mild conditions, facilitating the attachment of biomolecules to solid supports or nanoparticles with high efficiency.

Application

Cystamine serves as a versatile bifunctional thiol reagent, enabling efficient conjugation and crosslinking in peptide and protein engineering. Its dithiol structure facilitates disulfide bond formation under physiological conditions, offering reliable stability and controlled reactivity. Widely used in bioconjugation workflows, it supports the synthesis of antibody-drug conjugates and targeted delivery systems with high reproducibility.

Synthesis

  • Route1
    • null|null
      60-23-1
    • ~98%
    • In-stock
      Cystamine|CS-0086613
      51-85-4

    References

    • Hu, Nan Xing; Aso, Yoshio; Otsubo, Tetsuo; Ogura, Fumio Bulletin of the Chemical Society of Japan, 1986 , vol. 59, # 3 p. 879 - 884
  • Route2
    • null|null
      111238-66-5
    • ~88%
    • In-stock
      Cystamine|CS-0086613
      51-85-4

    References

    • Singh, Pramod K.; Field, Lamar Journal of Chemical & Engineering Data, 1988 , vol. 33, # 1 p. 67 - 68
  • Route3

    References

    • Kosmrlj, Janez; Kocevar, Marijan; Polanc, Slovenko Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 23 p. 3917 - 3919

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P312-P332+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.04
  • LogP   0.2852
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   5

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