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CS-W001157 4
Total: USD 88.00

3-Methoxybenzylamine

  • CAS No. 5071-96-5

  • Cat. No. CS-W007351
  • Purity≥97%
  • MDL No.MFCD00008115

*For research and further manufacturing use only, not for direct human use.

3-Methoxybenzylamine|CS-W007351

Structure of 5071-96-5

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General Information

  • CAS No. 5071-96-5
  • Cat. No. CS-W007351
  • Purity ≥97%
  • MDL No. MFCD00008115
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁NO
  • Molecular Weight None
  • Synonym(s) M-Methoxybenzylamine; 3-Methoxybenzylamine
  • SMILES C1=C(C=CC=C1OC)CN

Description

3-Methoxybenzylamine was used in the preparation of 6-substituted purines.

Application

3-Methoxybenzylamine serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and peptide conjugates. Its benzylamine scaffold offers reliable nucleophilicity and compatibility with standard coupling reactions, while the meta-methoxy substituent enhances solubility and modulates electronic properties. The compound exhibits good bench stability and is readily purified by distillation or chromatography, facilitating integration into multi-step synthetic sequences.

Synthesis

  • Route1
    • null|null
      1527-89-5
    • ~70%
    • In-stock
      3-Methoxybenzylamine|CS-W007351
      5071-96-5

    References

    • Gowda, Shankare; Gowda, D.Channe Tetrahedron, 2002 , vol. 58, # 11 p. 2211 - 2213
  • Route2
    • null|null
      153903-22-1
    • ~98%
    • In-stock
      3-Methoxybenzylamine|CS-W007351
      5071-96-5

    References

    • Lin; Lanza T.; De Laszlo; Truong; Kamenecka; Hagmann Tetrahedron Letters, 2000 , vol. 41, # 36 p. 7013 - 7016
  • Route3
    • N-(3-methoxybenzyl)acetamide|CS-0606723
      174688-81-4
    • ~%
    • In-stock
      3-Methoxybenzylamine|CS-W007351
      5071-96-5

    References

    • Carothers; Bickford; Hurwitz Journal of the American Chemical Society, 1927 , vol. 49, p. 2908

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.1539
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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