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CS-W001157 4
Total: USD 88.00

Tetrahydro-2H-thiopyran-4-carbaldehyde

  • CAS No. 50675-19-9

  • Cat. No. CS-0199595
  • Purity≥96%
  • MDL No.MFCD03425266

*For research and further manufacturing use only, not for direct human use.

Tetrahydro-2H-thiopyran-4-carbaldehyde|CS-0199595

Structure of 50675-19-9

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General Information

  • CAS No. 50675-19-9
  • Cat. No. CS-0199595
  • Purity ≥96%
  • MDL No. MFCD03425266
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀OS
  • Molecular Weight 130.21
  • Synonym(s) Tetrahydrothiopyran-4-carbaldehyde
  • SMILES C1CSCCC1C=O

Description

Tetrahydro-2H-thiopyran-4-carbaldehyde features a reactive aldehyde group tethered to a saturated thiacycle, offering a uniquely positioned functional handle for conjugation and cyclization. The sulfur atom enhances polarity and modulates reactivity, enabling selective transformations in synthetic sequences. This scaffold integrates readily into complex molecular architectures under mild conditions, delivering high functional group tolerance and stability during intermediate processing.

Application

Tetrahydro-2H-thiopyran-4-carbaldehyde serves as a versatile synthetic building block for heterocyclic scaffolds and functionalized intermediates. Its aldehyde functionality enables reliable transformations including reductive amination, Grignard additions, and Wittig reactions. The thiopyran ring provides stereochemical control and enhanced lipophilicity, beneficial in medicinal chemistry applications. Bench-stable and amenable to standard purification techniques, it facilitates efficient access to complex molecular architectures in multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   1.3285
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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