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CS-W001157 4
Total: USD 88.00

[Bis(2-diphenylphosphino)ethyl]ether

  • CAS No. 50595-38-5

  • Cat. No. CS-0108116
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

[Bis(2-diphenylphosphino)ethyl]ether|CS-0108116

Structure of 50595-38-5

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General Information

  • CAS No. 50595-38-5
  • Cat. No. CS-0108116
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₈H₂₈OP₂
  • Molecular Weight 442.47
  • Synonym(s) [Bis(2-diphenyL
  • SMILES P(CCOCCP(C1=CC=CC=C1)C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4

Description

Bis(2-diphenylphosphino)ethyl ether delivers a robust, bidentate phosphine ligand architecture with enhanced stability and solubility in organic media. This ether-bridged scaffold enables efficient coordination to transition metals, facilitating catalytic processes in cross-coupling and hydrogenation reactions under standard conditions.

Application

Bis(2-diphenylphosphino)ethyl ether serves as a versatile, bench-stable ligand in transition metal catalysis, enabling efficient cross-coupling reactions and homogeneous catalytic transformations. Its rigid, electron-rich diphosphine architecture enhances catalyst stability and selectivity in palladium- and nickel-catalyzed processes, facilitating C–C and C–heteroatom bond formations with broad functional group tolerance and straightforward purification.

Synthesis

  • Route1
    • In-stock
      Bis(2-bromoethyl) ether|CS-W014174
      5414-19-7
    • null|null
      829-85-6
    • ~43%
    • In-stock
      [Bis(2-diphenylphosphino)ethyl]ether|CS-0108116
      50595-38-5

    References

    • Bolzati, Cristina; Boschi, Alessandra; Uccelli, Licia; Tisato, Francesco; Refosco, Fiorenzo; Cagnolini, Aldo; Duatti, Adriano; Prakash, Sushumna; Bandoli, Giuliano; Vittadini, Andrea Journal of the American Chemical Society, 2002 , vol. 124, # 38 p. 11468 - 11479

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   5.2688
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   10

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