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Structure of 50332-66-6
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3-Nitroquinolin-4-ol features a quinoline core bearing a nitro group at the 3-position and a hydroxyl at the 4-position, creating a rigid, electron-deficient scaffold. This arrangement enables direct participation in transition-metal-catalyzed cross-couplings and facilitates hydrogen bonding in supramolecular architectures. The compound exhibits bench-stable handling under standard conditions.
3-Nitroquinolin-4-ol serves as a versatile building block in medicinal chemistry, enabling direct access to quinoline-based pharmacophores. Its dual functionality—nitro group at C3 and hydroxyl at C4—facilitates selective transformations, including reduction, coupling, and cyclization reactions. The compound exhibits good bench stability and compatibility with common protecting group strategies, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: