Lot numbers can be found on the outside label of a product:
2,4,6-Trichloropyrimidine-5-carbaldehyde
-
CAS No. 50270-27-4
- Cat. No. CS-M0311
- Purity≥98%
- MDL No.MFCD02257700
*For research and further manufacturing use only, not for direct human use.
Structure of 50270-27-4
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 50270-27-4
- Cat. No. CS-M0311
- Purity ≥98%
- MDL No. MFCD02257700
- Storage -20°C, sealed storage, away from moisture
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₅HCl₃N₂O
- Molecular Weight 211.43
- Synonym(s) 5-Pyrimidinecarboxaldehyde, 2,4,6-trichloro-
- SMILES ClC1=NC(Cl)=NC(Cl)=C1C([H])=O
Description
2,4,6-Trichloropyrimidine-5-carbaldehyde features a highly electrophilic aldehyde group flanked by three chlorine atoms on the pyrimidine ring, enabling selective conjugation in heterocyclic synthesis. This electron-deficient scaffold integrates readily into bioactive molecule frameworks, particularly in medicinal chemistry and agrochemical development.
Application
2,4,6-Trichloropyrimidine-5-carbaldehyde serves as a versatile building block in medicinal and synthetic chemistry, enabling efficient construction of heterocyclic scaffolds. Its aldehyde functionality reacts readily with amines and nucleophiles under mild conditions, while the trichloropyrimidine core offers high reactivity for substitution reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in API development and library generation.
Synthesis
-
Route1
-
68-12-2 -
67-52-7
- ~59%
-
In-stock
50270-27-4
References
-
Ye, Chengfeng; Gao, Haixiang; Boatz, Jerry A.; Drake, Gregory W.; Twamley, Brendan; Shreeve, Jean'ne M. Angewandte Chemie - International Edition, 2006 , vol. 45, # 43 p. 7262 - 7265
-
-
Route2
-
67-52-7
-
68-12-2
- ~91%
-
In-stock
50270-27-4
References
-
Borzsonyi, Gabor; Beingessner, Rachel L.; Yamazaki, Takeshi; Cho, Jae-Young; Myles, Andrew J.; Malac, Marek; Egerton, Ray; Kawasaki, Masahiro; Ishizuka, Kazuo; Kovalenko, Andriy; Fenniri, Hicham Journal of the American Chemical Society, 2010 , vol. 132, # 43 p. 15136 - 15139
-
-
Route3
-
67-52-7
-
28509-24-2
- ~%
-
In-stock
50270-27-4
References
-
Binggeli, Alfred; Maerki, Hans-Peter; Masquelin, Thierry; Mutel, Vincent; Wilhelm, Maurice; Wostl, Wolfgang Patent: US2003/60466 A1, 2003 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 42.85
- LogP 2.2493
- H_Acceptors 3
- H_Donors 0
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2,4,6-Trichloropyrimidine-5-carbaldehyde sigma2,4,6-Trichloropyrimidine-5-carbaldehyde manufacturer2,4,6-Trichloropyrimidine-5-carbaldehyde price2,4,6-Trichloropyrimidine-5-carbaldehyde structure2,4,6-Trichloropyrimidine-5-carbaldehyde SDSbuy 2,4,6-Trichloropyrimidine-5-carbaldehyde2,4,6-Trichloropyrimidine-5-carbaldehyde supplier2,4,6-Trichloropyrimidine-5-carbaldehyde uses2,4,6-Trichloropyrimidine-5-carbaldehyde molecular weightprice of 2,4,6-Trichloropyrimidine-5-carbaldehyde2,4,6-Trichloropyrimidine-5-carbaldehyde chemical name formula of 2,4,6-Trichloropyrimidine-5-carbaldehyde