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CS-W001157 4
Total: USD 88.00

Ethyl 2-fluoro-4-methylbenzoate

  • CAS No. 500579-61-3

  • Cat. No. CS-0059875
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-fluoro-4-methylbenzoate|CS-0059875

Structure of 500579-61-3

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General Information

  • CAS No. 500579-61-3
  • Cat. No. CS-0059875
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁FO₂
  • Molecular Weight 182.19
  • Synonym(s) benzoic acid,2-fluoro-4-methyl-,ethyl ester
  • SMILES C=1(C(=O)OCC)C(=CC(C)=CC1)F

Description

Ethyl 2-fluoro-4-methylbenzoate is a fluorinated aromatic ester featuring a para-methyl group and a meta-fluorine substitution on the benzene ring. This electron-deficient aryl moiety integrates readily into synthetic sequences requiring orthogonal reactivity, offering enhanced stability under standard bench conditions.

Application

Ethyl 2-fluoro-4-methylbenzoate serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct incorporation of fluorinated aromatic motifs. Its ortho-fluoro substituent facilitates subsequent cross-coupling reactions, while the ester group offers compatibility with standard transformations such as hydrolysis, reduction, or nucleophilic substitution. Bench-stable and readily purified by distillation or column chromatography, it functions efficiently in both small-scale exploratory synthesis and scalable process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   2.31082
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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