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CS-W001157 4
Total: USD 88.00

Cyclohexanamine hydrochloride

  • CAS No. 4998-76-9

  • Cat. No. CS-W013335
  • Purity≥98%
  • MDL No.MFCD00050540

*For research and further manufacturing use only, not for direct human use.

Cyclohexanamine hydrochloride|CS-W013335

Structure of 4998-76-9

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General Information

  • CAS No. 4998-76-9
  • Cat. No. CS-W013335
  • Purity ≥98%
  • MDL No. MFCD00050540
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄ClN
  • Molecular Weight 135.64
  • Synonym(s) None
  • SMILES NC1CCCCC1.Cl

Description

Cyclohexanamine hydrochloride serves as a stable, moisture-tolerant amine source for synthetic transformations. This bench-stable salt facilitates efficient incorporation into pharmaceutical intermediates and functional materials, offering predictable reactivity in nucleophilic substitution and condensation processes.

Application

Cyclohexanamine hydrochloride serves as a versatile building block in medicinal chemistry and process synthesis, enabling efficient access to nitrogen-containing scaffolds. Its stable salt form ensures ease of handling and purification, while the amine functionality readily participates in alkylation, acylation, and reductive amination reactions. The compound functions as a key intermediate in the construction of heterocyclic frameworks and bioactive molecules, offering consistent reactivity and compatibility with standard synthetic protocols.

Synthesis

  • Route1
    • null|null
      108-91-8
    • ~98%
    • In-stock
      Cyclohexanamine hydrochloride|CS-W013335
      4998-76-9

    References

    • Kuwahara, Yuki; Zhang, Ailing; Soma, Haruka; Tsuda, Akihiko Organic Letters, 2012 , vol. 14, # 13 p. 3376 - 3379
  • Route2
    • null|null
      126424-21-3
    • ~94%
    • In-stock
      Cyclohexanamine hydrochloride|CS-W013335
      4998-76-9

    References

    • Grieco, Paul A.; Clark, Jerry D. Journal of Organic Chemistry, 1990 , vol. 55, # 8 p. 2271 - 2272
  • Route3

    References

    • Miyamoto, Kazunori; Sakai, Yuuta; Goda, Shunsuke; Ochiai, Masahito Chemical Communications, 2012 , vol. 48, # 7 p. 982 - 984

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.6996
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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