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CS-W001157 4
Total: USD 88.00

Benzyl-PEG1-Tos

  • CAS No. 4981-83-3

  • Cat. No. CS-0064453
  • Purity≥98%
  • MDL No.MFCD00027610
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Benzyl-PEG1-Tos|CS-0064453

Structure of 4981-83-3

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Description

Benzyl-PEG1-Tos serves as a reactive linker for conjugation workflows, featuring a tosylate group that facilitates efficient coupling with nucleophiles. The benzyl-protected PEG1 spacer provides enhanced solubility and stability under standard conditions, enabling straightforward integration into peptide or small-molecule synthesis.

Application

Benzyl-PEG1-Tos serves as a versatile bifunctional building block for peptide and small-molecule conjugation. The benzyl group provides a stable, orthogonal handle for selective deprotection, while the PEG1 spacer offers enhanced solubility and reduced aggregation. The tosyl (Tos) group functions as a reliable leaving group in nucleophilic substitution reactions, enabling efficient coupling under mild conditions. This compound facilitates site-specific modifications in synthetic chemistry workflows with excellent bench stability and straightforward purification.

General Information

  • CAS No. 4981-83-3
  • Cat. No. CS-0064453
  • Purity ≥98%
  • MDL No. MFCD00027610
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₈O₄S
  • Molecular Weight 306.38
  • Synonym(s) None
  • SMILES CC1=CC=C(S(OCCOCC2=CC=CC=C2)(=O)=O)C=C1

Computational Chemistry Data

  • TPSA   52.6
  • LogP   2.91712
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   7

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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