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CS-W001157 4
Total: USD 88.00

2-Azabicyclo[2.2.1]hept-5-en-3-one

  • CAS No. 49805-30-3

  • Cat. No. CS-W019811
  • Purity≥98%
  • MDL No.MFCD00213364

*For research and further manufacturing use only, not for direct human use.

2-Azabicyclo[2.2.1]hept-5-en-3-one|CS-W019811

Structure of 49805-30-3

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General Information

  • CAS No. 49805-30-3
  • Cat. No. CS-W019811
  • Purity ≥98%
  • MDL No. MFCD00213364
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇NO
  • Molecular Weight 109.13
  • Synonym(s) (±)-Vince lactam; Rac-Vince lactam; Vince lactam; 4-Amino-2-cyclopentene-1-carboxylic Acid Lactam; 2-Azabicyclo[2.2.1]hept-5-en-3-one
  • SMILES O=C1NC2C=CC1C2

Description

2-Azabicyclo[2.2.1]hept-5-en-3-one is also referred as vince lactam. It is a versatile intermediate in the synthesis of carbocyclic nucleosides. 2-Azabicyclo[2.2.1]hept-5-en-3-one and its monohydrated complex was investigated in a supersonic jet by Fourier transform microwave spectroscopy.2-Azabicyclo[2.2.1]hept-5-en-3-one was used in:preparation of (3aS,4R,6R,6aR)-6-((methoxy-methoxy)methyl)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-amine, a precursor of analog of bredininsynthesis of therapeutic drugschemoenzymatic synthesis of ()-carbovir

Synthesis

  • Route1
    • null|null
      19158-51-1
    • ~78%
    • In-stock
      2-Azabicyclo[2.2.1]hept-5-en-3-one|CS-W019811
      49805-30-3

    References

    • Kuraray Co., Ltd. Patent: US6060609 A1, 2000 ;
  • Route2
    • Methanesulfonyl cyanide|CS-0263273
      24225-08-9
    • null|null
      542-92-7
    • ~%
    • In-stock
      2-Azabicyclo[2.2.1]hept-5-en-3-one|CS-W019811
      49805-30-3

    References

    • Lonza Ltd. Patent: US5200527 A1, 1993 ;
  • Route3
    • null|null
      19158-51-1
    • null|null
      542-92-7
    • ~56%
    • In-stock
      2-Azabicyclo[2.2.1]hept-5-en-3-one|CS-W019811
      49805-30-3

    References

    • Heesing, Albert; Herdering, Wilhelm Chemische Berichte, 1983 , vol. 116, # 3 p. 1081 - 1096

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   0.0609
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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