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CS-W001157 4
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tert-Butyl 4-(5-iodopyridin-2-yl)piperazine-1-carboxylate

  • CAS No. 497915-42-1

  • Cat. No. CS-0134711
  • Purity≥98%
  • MDL No.MFCD07781193

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4-(5-iodopyridin-2-yl)piperazine-1-carboxylate|CS-0134711

Structure of 497915-42-1

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General Information

  • CAS No. 497915-42-1
  • Cat. No. CS-0134711
  • Purity ≥98%
  • MDL No. MFCD07781193
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₀IN₃O₂
  • Molecular Weight 389.23
  • Synonym(s) 1-Boc-4-(5-Iodo-2-Pyridyl)Piperazine
  • SMILES O=C(OC(C)(C)C)N1CCN(CC1)C2=NC=C(C=C2)I

Synthesis

  • Route1
    • tert-Butyl 4-(pyridin-2-yl)piperazine-1-carboxylate|CS-0209940
      77278-62-7
    • ~%
    • tert-Butyl 4-(5-iodopyridin-2-yl)piperazine-1-carboxylate|CS-0134711
      497915-42-1

    References

    • WO2008/62276 A2, ; Page/Page column 50 ; WO 2008/062276 A2
  • Route2

    References

    • Bioorganic and Medicinal Chemistry, , vol. 15, # 4 p. 1586 - 1605

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   45.67
  • LogP   2.7433
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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